Published: Wed, January 10, 2018
Health Care | By Gwendolyn Kim

Ibuprofen can cause male infertility

Ibuprofen can cause male infertility

A new study is hinting that a common over-the-counter painkiller, ibuprofen, may be linked to a male reproductive disorder. (Longer term, lower testosterone would affect this, too.) A few other groups of genes involved in different testicular processes were also unaffected.

Infertility in men can be caused by a variety of factors including trauma, genetic and hormonal disorders, age, weight, smoking, drug and alcohol use, and environmental toxins.

The hormonal imbalance caused compensated hypogonadism, which is a condition linked to decreased male fertility, depression, and an increased risk of heart attack or stroke.

Researchers looked at 31 male participants and found that taking ibuprofen reduced production of testosterone by almost a quarter in the space of around six weeks.

The researchers found that, compared with the placebo group, the men who took ibuprofen experienced a 23 percent increase in levels of luteinizing hormone (LH) - a hormone that's secreted by the pituitary gland and stimulates the production of testosterone - after two weeks. Samples were taken before and after the trial for comparison.

"We normally see this condition in elderly men, so it raises an alarm", study co-author Bernard Jégou of the French National Institute of Health and Medical Research, told The Guardian. This is more common in older men than younger ones.

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They tracked how ibruprofen affected them, noting that the painkiller can affect your body's hormone levels.

'Several studies have shown mild analgesics exposure during foetal life is associated with anti-androgenic effects and congenital malformations. Otherwise, occasional use at the recommended dosage to treat aches and pains is safe and recommended.

Previous research by European scientists showed that male babies whose mothers took ibuprofen experienced disturbances to their endocrine system, according to CNN. The authors speculate that this could have health implications for such men, given the known links between the disruption of such hormones and cardiovascular disease, diabetes and infertility. Of course, there is a bright side to this new finding, and that is to limit your intake of ibuprofen.

The study was first tested on women, according to CNN. Unfortunately, a new study says that ibuprofen can actually reduce fertility rates in men.

"Long-term use of ibuprofen has other negative effects on overall health so people should only be taking it over a period of weeks, months or years if a doctor has prescribed it".

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